Selim DEMİRCİ, Özgür ÇINAR, Burcu Nilgün ÇETİNER, Mehmet Masum TÜNÇAY, Arif Nihat GÜLLÜOĞLU
Bioglass® (Bioglass 45S5) as the third generation of biomaterials, has provided tissue regeneration and repair due to its gene activation properties since its discovery in 1969. Y3Fe5O12 (YIG) is an example of ferrimagnetic ceramics widely applied in passive microwave devices, for this study it was used as a candidate material for hyperthermia treatment of cancer. In this study, the Bioglass® (Bioglass 45S5) was produced via the sol-gel method in order to obtain a better homogenous mixture and control of the composition, and also to attain a high level of amorphism. The resultant sol was maintained at room temperature for about 14 days, aged at 70 oC for 72 h, and finally dried in an oven at 130 oC for 48 h, allowing the removal of gaseous by-products. In the following, the obtained product has been designed as-dried. The dried powders were then mixed with 1-3 wt. % YIG powders, which was produced similarly via citrate gel process, dried initially at 120 oC for 24 h and further heat-treated in the air at 1000 oC, then ground to finer powder, using ball milling. Pellets of 1-inch diameter were obtained using the uniaxial manual press (2000 psi force was applied) and sintered at 900 oC for 2 hours along with some mixed powder into alumina crucibles. XRD analysis of the powder specimens after sintering was performed. Some of the obtained glass-ceramic composite specimens were first molded and polished, then the surface hardness measurements were taken. The other specimens were heat-treated for thermal etching at 800 oC and further molded, polished, and visualized.

Anahtar Kelimeler: Bioglass®, YIG (yttrium iron garnet), sol-gel, citrate gel, characterization